Example of Laser-microdissection of pancreatic ductal adenocarcinoma tissues using the LMD7000 instrument (Leica Microsystems, Wetzlar, Germany, thanks to the help of Dr. Mauro Baron). The precision of the narrow focus of the laser beam allowed to pickup specimens with high degree of accuracy and extremely low risk of contamination.
This video has been published as supplemental file to the article:
Giovannetti E, Funel N, Peters GJ, Del Chiaro M, Erozenci LA, Vasile E, Leon LG, Pollina LE, Groen A, Falcone A, Danesi R, Campani D, Verheul HM, Boggi U.
MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity
Cancer Res. 2010;70:4528-38